COLLABORATION WITH DR. J. C.-Y LEE
Dr. Jetty Chung Yung Lee is working in the Lipid Metabolism Laboratory in Hong-Kong University (Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong).
Dr. Lee is analytical chemist specialized in the quantification of oxylipins using lipidomic approach. Her research focuses on lipid peroxidation and profiling of biological samples. She develops measurement of oxidative damage biomarkers in biological samples using GC/MS and LC-MS/MS and investigates the association of these biomarkers in diseases. Her interest also includes antioxidant and oxidative stress in human nutrition and oxidative stress and environmental stressors (climate change and pollutants).
Our work in collaboration
The effect of perfluorooctane sulfonate (PFOS) exposure in utero was looked in mouse testis. PUFAs were quantitated as well as their metabolites, showing the formation of furanic compounds under high oxygen tension.
See publication 52 about this work.
First report of alpha-linolenic acid peroxidation into furanic metabolites, named phytofurans. Phytofurans were highlighted for the first time in seeds (Pine, Walnut, Chia, Flax), by LC/MS-MS.
See publication 28 about this work
The discovery of the peroxidation of adrenic acid (AdA) in the brain of pre-term pig, by LC/MS-MS quantitation of AdA metabolites named dihomo-Isofurans.
Dihomo-Isofurans and Neurofurans were also quantitated in the heart and brain of rats.
See publications 15, 22 about this work
The collaboration with Dr. Lee focused on the quantification of oxylipins in food matrices, in human biological samples have led to more than 20 articles (n° 20, 23-25, 28, 31, 34, 39, 40, 44, 49-53, 57, 69, 71, 76, 77, 82, 108, 121).
Working since 2014 with Dr. Lee, our strong collaboration goes all around Asia. Indeed, Dr. Lee permitted our team access to other research teams in Asia working on oxidative stress. In 2020, we developed a collaboration with Dr. Taihun Kim at KIOT (Jeju, Korea).