TOTAL SYNTHESIS OF ISOFURANOIDS

    FIRST STRATEGY

     

    This strategy was developed in 2014 and allowed an efficient access to dihomo-isofuran and neurofuran derivatives from the alkenyl and enediol family. 

    Télécharger
    Have a quick look on our first strategy
    Isofuranoid strategy 1.pdf
    Document Adobe Acrobat 682.6 KB
    Télécharger

    For more details see pdf below and publications 15 and 22 


    SECOND STRATEGY

     

    The strategy developed in 2015 allowed an efficient access to phytofuran derivatives from the alkenyl and enediol family.

    Télécharger
    Have a quick look on our second strategy
    Isofuranoid strategy 2.pdf
    Document Adobe Acrobat 690.6 KB
    Télécharger

    For more details see publications 28 and 49

    THIRD STRATEGY

     

    This strategy was developed in the beginning of 2022. Our first stragegy planned to used organocatalysis to build the cyclic core, but our journey was quite suprising. We succeed to develop a racemic strategy and access two enediol structures from stearidonic acid.

     

    This work will soon be published!

    Télécharger
    Have a quick look on our third strategy
    Third Strategy IsoFs.pdf
    Document Adobe Acrobat 325.1 KB
    Télécharger

    ALL ISOFURANOIDS AVAILABLE

     

    Thanks to our synthetic strategies several furanoids are available in our laboratory.

     

    People interested by these compounds as biomarkers of oxidative stress or to test their biological properties can contact us for collaboration.

    Télécharger
    List of isofuranoids
    List of isofuranoids.pdf
    Document Adobe Acrobat 271.9 KB
    Télécharger

    Go back to Research Page